This annual report provides key achievements of the CGIAR Research Program on Fish Agri-Food Systems (FISH) during 2019. The results of FISH during this year included: 1) the discovery of innovations for sustainable development of aquaculture and fisheries; 2) substantial contribution to policy influence and change across the fish agri-food system from national to global levels in Africa, Asia and the Pacific, and; 3) the delivery of improved livelihoods, nutrition and environmental outcomes to the users of FISH research, through a growing network of research collaborators and development partners. The emerging evidence and innovations from FISH are shedding light and laying a strong foundation for future impacts related to the global food systems transformation towards healthier and sustainable diets, where fish and aquatic foods have a considerable role to play.