This study presents a comprehensive site-scale analysis conducted within the global wetland inventory and mapping (GWIM) project. GWIM was developed and promoted by the International Water Management Institute (IWMI) through global partnerships to investigate wetland analyses at multiple scales. The present study investigates the complexity of an inland freshwater wetland system, presenting a conceptual framework for mapping and monitoring the dynamics of Lake Kolleru (a wetland of international importance, as defined by the Ramsar Convention), utilizing a geospatial platform. Illustrating the pace of land use changes leading to the progressive elimination of the wetland ecosystem of freshwater Lake Kolleru, this study also highlights the impacts of such changes on the socio-economic system.