The goal of the WorldFish-led project, “Scaling Systems and Partnerships for Accelerating the Adoption of Improved Tilapia Strains by Small-Scale Fish Farmers (SPAITS)”, is to increase the adoption of improved tilapia strains by poor fish producers and deliver improved productivity and profitability of small-scale aquaculture, so that, poor producers, particularly women, are enabled to exit poverty while improving natural resource systems to sustain future fish production. The project’s purpose is to design systems for accelerating the dissemination and adoption of improved tilapia strains and aquaculture management practices developed by WorldFish, based on relevant, gender sensitive and contextual knowledge, that will enable poor small-scale fish farmers to have access to, adopt and benefit from improved strains of tilapia. The project operates in three countries, Bangladesh, Malawi, and Myanmar from July 2018 to June 2021. This annual report covers the period from 1 January to 31 December 2020.