The purpose of this chapter is to present and discuss key conditions for the successful implementation of fisheries and coastal co-management identified in South-east Asia, Africa, the Pacific and the wider Caribbean. These four regions were selected as several recent research and development projects have produced outputs in which key conditions have been identified. The conditions are reported on a regional basis not for a specific country, as this is how the authors have presented their results. It is expected that specific conditions would differ by country. These conditions will embrace the wide range of aspects that can affect the implementation and performance of co-management and activities, from resources and fisheries to cultural and institutional dimensions. The chapter will conclude with a discussion of policy implications for fisheries and coastal co-management.