Innovation Platforms are an increasingly popular approach to enhancing multi-stakeholder collaboration in agricultural research for development (AR4D) programmes. Innovation Platforms facilitate interaction and collaboration within and between networks of farmers, governmental and non-governmental service providers, policymakers, researchers, private sector players, and other stakeholders in the agricultural system. As the implementation of Innovation Platforms can consume significant time, energy, and other resources, these guidelines are geared towards development practitioners, researchers, funding agencies, or farmer unions themselves interested in using Innovation Platforms in their AR4D or business development programmes.