Under the Regional Programme Fisheries and HIV/AIDS in Africa, implemented by the WorldFish Center in collaboration with FAO, this paper is the second in a series of papers that have been generated from reviewing literature on trends in consumption and processing of low-value fish products marketed in the Lake Victoria region. The papers fall under the programme’s research component in Uganda, analyzing nutritive quality and post-harvest activities in ‘low value’ fish market chains around Lake Victoria, focusing on Mukono District, Uganda. The objective of this review is to examine the common practices in processing, preservation, and storage of low-value fish products marketed in the Lake Victoria region and the impact of these practices on nutritional quality of these products and their contribution to populations at risk for malnutrition and people living with HIV/AIDS (PLHIV).