The WorldFish Center and the UN Food and Agriculture Organization (FAO) are currently implementing a Regional Programme entitled Fisheries and HIV/AIDS in Africa: Investing in Sustainable Solutions, to strengthen the capacity in the region to develop sustainable solutions to enhance the contributions of fish and fisheries to economic and human development. In particular, the programme is building a strategic response to HIV/AIDS in the fisheries sector that will generate benefits for vulnerable groups in wider society. With financial support from the Swedish-Norwegian Regional Programme on HIV/AIDS in Africa, this programme is conducting research-for-development activities and implementing pilot interventions in selected fishing communities in eight countries in sub-Saharan Africa, namely Benin, Democratic Republic of Congo (DRC), Cameroon, Nigeria, Malawi, Mozambique, Uganda and Zambia. In all eight countries, three technical focus areas have been identified through national consultations 1) Options for reducing vulnerability along the fish marketing chain; 2) Enhancing nutrition benefits from small scale aquaculture and fisheries; 3) Institutional change to increase investment in viable support options; This report presents initial findings by the Regional Programme, a regional synthesis and policy implications of these programme findings, and policy recommendations to address HIV/AIDS in the fisheries sector in Africa, as defined by the PAG members during its first meeting in Lilongwe.